Southampton’s cancer research expertise extends beyond immunology. Our scientists are leveraging artificial intelligence (AI) to enhance cancer diagnosis and treatment. This cutting-edge technology is already making a difference for patients at the University Hospital.

During the COVID-19 pandemic, a patient went to the hospital for a scan and routine endoscopy, only to receive a diagnosis of oesophageal cancer. “I was just extremely tired – sort of catatonic and I had difficulty in swallowing some foods,” they recall. The tumour, the size of a Starburst sweet, was a major blockage in their oesophagus.

The patient was placed under the care of Professor Tim Underwood, a University of Southampton professor of gastrointestinal surgery and research lead. Professor Underwood used a new AI modelling tool to prescribe a comprehensive treatment plan, including six weeks of chemotherapy, six weeks of radiotherapy, and a full oesophagectomy. This AI tool, developed in collaboration with the University’s computer scientists, helps predict a patient’s likely response to treatment. For the patient, the models suggested a high chance of a positive outcome.

The patient responded well to their treatment, with the models indicating a 3-5 year survival rate of around 90 percent. With no signs of cancer returning, they now looks forward to a long and healthy life. “When people find out that I’ve had cancer, they tell me I’m unlucky, but actually I’m one of the lucky ones. I was caught. I was treated and I was sent on my way.”

Professor Underwood’s work on AI models has been instrumental in selecting the right care plans for his patients. He believes AI is essential for improving cancer patient outcomes. “The application of AI, both in cancer and in other areas of medicine, informs the conversation around what the diagnosis might be and what treatment to offer to an individual.”

The University of Southampton remains committed to advancing cancer research and improving patient outcomes through innovative approaches and cutting-edge technology.